Summary

Name PRKAR2B
Full Name cAMP-dependent protein kinase type II-beta regulatory subunit
Synonyms KAP3_HUMAN
Primary ID P31323
Links - -
Type protein
Relations 6
Inhibitors 3',5'-cyclic AMP
Function Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png phosphorylation PRKAR2B 0.876
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation PRKAR2B 0.2
Publications: 1 Organism: Mus Musculus
+ down-regulates quantity by destabilization img/direct_inhibition.png polyubiquitination PRKAR2B 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding PRKACB 0.89
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png chemical inhibition PRKAR2B 0.8
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png binding PRKACA 0.876
Publications: 1 Organism: Homo Sapiens