+ |
PRKCE | up-regulates activity
phosphorylation
|
SLC4A3 |
0.314 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-249127 |
Ser67 |
EKPSRSYsERDFEFH |
Homo sapiens |
HEK-293 Cell |
pmid |
sentence |
11739292 |
We conclude that following Ang II stimulation of cells, PKCepsilon phosphorylates serine 67 of the AE3 cytoplasmic domain, inducing the Ang II-induced increase in anion transport observed in the hypertrophic myocardium. |
|
Publications: |
1 |
Organism: |
Homo Sapiens |
+ |
SLC4A3 | down-regulates quantity
relocalization
|
hydrogencarbonate |
0.8 |
Identifier |
Residue |
Sequence |
Organism |
Cell Line |
SIGNOR-264917 |
|
|
Homo sapiens |
Neuron |
pmid |
sentence |
26136660 |
Slc4a10 is a Na+-coupled Cl−-HCO3− exchanger, which is expressed in principal and inhibitory neurons as well as in choroid plexus epithelial cells of the brain. In neurons, bicarbonate transport is mainly mediated by members of the SLC4A family of proteins. While the Na+-independent anion-exchanger SLC4A3 lowers the intraneuronal bicarbonate concentration, the Na+-dependent anion exchangers SLC4A8 (NDCBE) and SLC4A10 (NCBE) use the sodium gradient to accumulate bicarbonate in exchange of chloride |
|
Publications: |
1 |
Organism: |
Homo Sapiens |