Summary

Name EFNA4
Full Name Ephrin-A4
Synonyms EPH-related receptor tyrosine kinase ligand 4, LERK-4 | EPLG4, LERK4
Primary ID P52798
Links - -
Type protein
Relations 1
Function Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. May play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding EPHA5 0.804
Publications: 1 Organism: Homo Sapiens