4.0
Summary
| Name |  MLLT10
|
| Full Name | Protein AF-10 |
| Synonyms | ALL1-fused gene from chromosome 10 protein | AF10 |
| Primary ID | P55197 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | MLLT10 | form complex 
binding
|
SS18/MLLT10 | 0.425 |
| Publications: | 1 | Organism: | Homo Sapiens | |