Summary

Name RAB14
Full Name Ras-related protein Rab-14
Synonyms RAB14_HUMAN |
Primary ID P61106
Links - -
Type protein
Relations 2
Function Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes (By similarity). Regulates, together with its guanine nucleotide exchange factor DENND6A, the specific endocytic transport of ADAM10, N-cadherin/CDH2 shedding and cell-cell adhesion.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png relocalization RUFY1 0.612
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding Early Endosome 0.41
Publications: 1 Organism: Homo Sapiens