3.0
Summary
| Name |  EIF4A2
|
| Full Name | Eukaryotic initiation factor 4A-II |
| Synonyms | eIF-4A-II, eIF4A-II, ATP-dependent RNA helicase eIF4A-2 | DDX2B, EIF4F |
| Primary ID | Q14240 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | EIF4A2 | form complex 
binding
|
eIF4F_complex | 0.812 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| Tissue: | Kidney | |||