Summary

Name DRAP1
Full Name Dr1-associated corepressor
Synonyms Dr1-associated protein 1, Negative cofactor 2-alpha, NC2-alpha
Primary ID Q14919
Links - -
Type protein
Relations 2
Function The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding NC2 complex 0.78
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding BTAF1 0.526
Publications: 1 Organism: Oryctolagus Cuniculus