3.0
Summary
| Name |  SHPRH
|
| Full Name | E3 ubiquitin-protein ligase SHPRH |
| Synonyms | SNF2, histone-linker, PHD and RING finger domain-containing helicase | KIAA2023 |
| Primary ID | Q149N8 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'. |
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ubiquitination