3.0
Summary
| Name |  TAF1C
|
| Full Name | TATA box-binding protein-associated factor RNA polymerase I subunit C |
| Synonyms | RNA polymerase I-specific TBP-associated factor 110 kDa, TAFI110, TATA box-binding protein-associated factor 1C, TBP-associated factor 1C, Transcription initiation factor SL1/TIF-IB subunit C | |
| Primary ID | Q15572 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits. Recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | TAF1C | form complex 
binding
|
SL1 complex | 0.796 |
| Publications: | 1 | Organism: | Homo Sapiens | |