Summary

Name H2BC21
Full Name Histone H2B type 2-E
Synonyms H2B-clustered histone 21, Histone H2B-GL105, Histone H2B.q, H2B/q | H2BFQ, HIST2H2BE
Primary ID Q16778
Links - -
Type protein
Relations 4
Function Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; FUNCTION

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png monoubiquitination H2BC21 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png monoubiquitination H2BC21 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation H2BC21 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates quantity by expression img/direct-activation.png translation regulation H2BC21 0.2
Publications: 1 Organism: Homo Sapiens