Summary

Name LTC4S
Full Name Leukotriene C4 synthase
Synonyms LTC4 synthase, Leukotriene-C(4) synthase |
Primary ID Q16873
Links - -
Type protein
Relations 1
Function Catalyzes the conjugation of leukotriene A4 with reduced glutathione (GSH) to form leukotriene C4 with high specificity (PubMed:7937884, PubMed:27791009, PubMed:27365393, PubMed:9153254, PubMed:23409838). Can also catalyzes the transfer of a glutathionyl group from glutathione (GSH) to 13(S),14(S)-epoxy-docosahexaenoic acid to form maresin conjugate in tissue regeneration 1 (MCTR1), a bioactive lipid mediator that possess potent anti-inflammatory and proresolving actions (PubMed:27791009).

Viewer

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations

Regulator Mechanism target score ℹ
+ NfKb-p65/p50down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation LTC4S 0.262
Publications: 1 Organism: Homo Sapiens