4.0
Summary
| Name |  FIGNL1
|
| Full Name | Fidgetin-like protein 1 |
| Synonyms | FIGL1_HUMAN | |
| Primary ID | Q6PIW4 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Involved in DNA double-strand break (DBS) repair via homologous recombination (HR). Recruited at DSB sites independently of BRCA2, RAD51 and RAD51 paralogs in a H2AX-dependent manner. May regulate osteoblast proliferation and differentiation (PubMed:23754376). May play a role in the control of male meiosis dynamic (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | FIGNL1 | form complex 
binding
|
FLIP-FIGNL1 DNA interstrand crosslink repair complex | 0.2 |
| Publications: | 1 | Organism: | Homo Sapiens | |