3.0
Summary
| Name |  WDR59
|
| Full Name | GATOR complex protein WDR59 |
| Synonyms | WD repeat-containing protein 59 | KIAA1923 |
| Primary ID | Q6PJI9 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210). |
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ubiquitination
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