4.0
Summary
| Name |  SUPT20H
|
| Full Name | Transcription factor SPT20 homolog |
| Synonyms | p38-interacting protein, p38IP | C13orf19, FAM48A |
| Primary ID | Q8NEM7 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail (By similarity). Required for starvation-induced ATG9A trafficking during autophagy. |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | SUPT20H | form complex 
binding
|
SAGA complex | 0.749 |
| Publications: | 1 | Organism: | Homo Sapiens | |