4.0
Summary
| Name |  HAS1
|
| Full Name | Hyaluronan synthase 1 |
| Synonyms | Hyaluronate synthase 1, Hyaluronic acid synthase 1, HA synthase 1, HuHAS1 | HAS |
| Primary ID | Q92839 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential for the synthesis of hyaluronan, a major component of most extracellular matrices that has a structural role in tissue architecture and regulates cell adhesion, migration and differentiation. This is one of the isozymes catalyzing that reaction. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate (By similarity). |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | HAS1 | form complex 
binding
|
HAS1-HAS2 hyaluronan biosynthesis complex | 0.326 |
| Publications: | 1 | Organism: | Homo Sapiens | |