3.0
Summary
| Name |  CLP1
|
| Full Name | Polyribonucleotide 5'-hydroxyl-kinase Clp1 |
| Synonyms | Polyadenylation factor Clp1, Polynucleotide kinase Clp1, Pre-mRNA cleavage complex II protein Clp1 | HEAB |
| Primary ID | Q92989 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double-stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Plays a key role in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex |
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Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | CLP1 | form complex 
binding
|
CFII complex | 0.885 |
| Publications: | 1 | Organism: | Homo Sapiens | |