| + |
TRIM47 | down-regulates quantity
ubiquitination
|
CYLD |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-266443 |
|
|
Mus musculus |
Hepatocyte |
| pmid |
sentence |
| 29291351 |
CYLD is progressively degraded upon interaction with the E3 ligase TRIM47 in proportion to NASH severity |
|
| Publications: |
1 |
Organism: |
Mus Musculus |
| + |
Ub:E2 | up-regulates activity
ubiquitination
|
TRIM47 |
0.2 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-271001 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 34199813 |
The ubiquitination process is mediated sequentially by three classes of enzymes consisting of a Ub-activating enzyme E1, a Ub-conjugating enzyme E2, and a Ub ligase E3. Ub is first activated by E1 in an adenosine 5′-triphosphate (ATP)-dependent manner t |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |