Summary

Name PHOX2B
Full Name Paired mesoderm homeobox protein 2B
Synonyms Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B | PMX2B
Primary ID Q99453
Links - -
Type protein
Relations 1
Function Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

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Relations

Regulator Mechanism target score
+ down-regulates img/direct_inhibition.png ubiquitination PHOX2B 0.58
Publications: 1 Organism: Homo Sapiens