4.0
Summary
| Name |  SH3GL2View Modifications |
| Full Name | Endophilin-A1 |
| Synonyms | EEN-B1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2 | CNSA2, SH3D2A |
| Primary ID | Q99962 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Required for BDNF-dependent dendrite outgrowth. Cooperates with SH3GL2 to mediate BDNF-NTRK2 early endocytic trafficking and signaling from early endosomes. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | LRRK2 | down-regulates 
phosphorylation
|
SH3GL2 | 0.471 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | ROCK2 | down-regulates
phosphorylation
|
SH3GL2 | 0.441 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | SH3GL2 | up-regulates 
|
Endocytosis | 0.7 |
| Publications: | 1 | Organism: | Homo Sapiens | |