Summary

Name MYBBP1A
Full Name Myb-binding protein 1A
Synonyms MBB1A_HUMAN | P160
Primary ID Q9BQG0
Links - -
Type protein
Relations 3
Function May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity). Has a role in rRNA biogenesis together with PWP1 (PubMed:29065309).

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Modifications Tables

Relations

Regulator Mechanism target score
+ img/unknown.png phosphorylation MYBBP1A 0.395
Publications: 1 Organism: Homo Sapiens
+ form complex img/form-complex.png binding B-WICH complex 0.468
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding MYBBP1A 0.2
Publications: 1 Organism: In Vitro