3.0
Summary
| Name |  PDCD10View Modifications |
| Full Name | Programmed cell death protein 10 |
| Synonyms | Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15 | CCM3, TFAR15 |
| Primary ID | Q9BUL8 |
| Links |  -  -  |
| Type | protein |
| Relations | 4 |
| Function | Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity (PubMed:27807006). Important for cell migration, and for normal structure and assembly of the Golgi complex (PubMed:27807006). Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity). |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | STK25 |
phosphorylation
|
PDCD10 | 0.791 |
| Publications: | 2 | Organism: | Homo Sapiens | |
| + | PTPN13 | down-regulates activity 
dephosphorylation
|
PDCD10 | 0.585 |
| Publications: | 1 | Organism: | Homo Sapiens | |
| + | PTPN13 | down-regulates
dephosphorylation
|
PDCD10 | 0.585 |
| Publications: | 1 | Organism: | Homo Sapiens | |