Relation Results

Summary

Name DDX23
Full Name Probable ATP-dependent RNA helicase DDX23
Synonyms 100 kDa U5 snRNP-specific protein, DEAD box protein 23, PRP28 homolog, U5-100kD |
Primary ID Q9BUQ8
Links - -
Type protein
Relations 1
Function Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation (PubMed:18425142). Independently ...
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Type: Score: Layout: SPV 
0.725DDX23U4/U6.U5 snRNP complex

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Relations
Regulator
Mechanism
target
score ℹ
+ DDX23form complex img/form-complex.png binding U4/U6.U5 snRNP complex 0.725
Identifier Residue Sequence Organism Cell Line
SIGNOR-270646 Homo sapiens
pmid sentence
The major spliceosomal building blocks are the U1, U2, U4/U6, and U5 small nuclear ribonucleoproteins (snRNPs). Each consists of a small nuclear RNA (snRNA) (or two, in the case of U4/U6), seven Sm proteins that form a ring (or seven Lsm proteins in the case of U6), and a variable number of snRNP-specific proteins (Fig. 1F) (Will and Lührmann 2011). Under splicing conditions, the U4/U6 and U5 snRNPs form a 25S U4/U6.U5 tri-snRNP, in which the U4 and U6 snRNAs are base-paired, forming a three-way junction.
Publications: 1 Organism: Homo Sapiens
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