Summary

Name POLDIP3
Full Name Polymerase delta-interacting protein 3
Synonyms 46 kDa DNA polymerase delta interaction protein, p46, S6K1 Aly/REF-like target, SKAR | KIAA1649, PDIP46
Primary ID Q9BY77
Links - -
Type protein
Relations 3
Function Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by association with the TREX complex.

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Modifications Tables

Relations

Regulator Mechanism target score
+ img/unknown.png phosphorylation POLDIP3 0.758
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png binding TREX complex 0.6
Publications: 1 Organism: Homo Sapiens