Summary

Name PDGFD
Full Name Platelet-derived growth factor D
Synonyms PDGF-D, Iris-expressed growth factor, Spinal cord-derived growth factor B, SCDGF-B | IEGF, SCDGFB
Primary ID Q9GZP0
Links - -
Type protein
Relations 0
Function Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix (By similarity).

Viewer