Summary

Name SDHAF2
Full Name Succinate dehydrogenase assembly factor 2, mitochondrial
Synonyms SDH assembly factor 2, SDHAF2 | C11orf79, PGL2, SDH5
Primary ID Q9NX18
Links - -
Type protein
Relations 1
Function Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding SDHB 0.644
Publications: 1 Organism: Homo Sapiens