4.0
Summary
| Name |  COQ3
|
| Full Name | Ubiquinone biosynthesis O-methyltransferase, mitochondrial |
| Synonyms | 3-demethylubiquinol 3-O-methyltransferase, 2.1.1.64, 3-demethylubiquinone 3-O-methyltransferase, 2.1.1.-, Polyprenyldihydroxybenzoate methyltransferase, 2.1.1.114 | |
| Primary ID | Q9NZJ6 |
| Links |  -  -  |
| Type | protein |
| Relations | 1 |
| Function | O-methyltransferase required for two non-consecutive steps during ubiquinone biosynthesis (By similarity) (PubMed:10777520, PubMed:38425362). Catalyzes the 2 O-methylation of 3,4-dihydroxy-5-(all-trans-decaprenyl)benzoic acid into 4-hydroxy-3-methoxy-5-(all-trans-decaprenyl)benzoic acid (By similarity) (PubMed:10777520, PubMed:38425362). Also catalyzes the last step of ubiquinone biosynthesis by mediating methylation of 3-demethylubiquinone into ubiquinone (By similarity) (PubMed:38425362). Also able to mediate the methylation of 3-demethylubiquinol-10 into ubiquinol-10 (By similarity) (PubMed:10777520). |
Viewer
Search Tools
Refine search:
- by mechanism
- by effect
- by organism:
- by tissue:
- by cell-line
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | COQ3 | form complex 
binding
|
CoQ biosynthetic complex | 0.654 |
| Publications: | 1 | Organism: | Homo Sapiens | |