3.0
Summary
| Name |  Ncor2
|
| Full Name | Nuclear receptor corepressor 2 |
| Synonyms | N-CoR2, Silencing mediator of retinoic acid and thyroid hormone receptor, SMRT, SMRTe, T3 receptor-associating factor, TRAC, Thyroid-, retinoic-acid-receptor-associated corepressor | Smrt |
| Primary ID | Q9WU42 |
| Links |  -  -  |
| Type | protein |
| Relations | 0 |
| Function | Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival. |