Summary

Name RXYLT1
Full Name Ribitol-5-phosphate xylosyltransferase 1
Synonyms TMEM5_HUMAN |
Primary ID Q9Y2B1
Links - -
Type protein
Relations 1
Function UDP-xylosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity (PubMed:25279699, PubMed:27601598, PubMed:27733679) (Probable). Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan (PubMed:27733679, PubMed:29477842) (Probable).

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Relations

Regulator Mechanism target score ℹ
+ RXYLT1form complex img/form-complex.png binding Fukutin-FKRP-TMEM5 multienzyme complex 0.2
Publications: 1 Organism: Homo Sapiens