Relation Results

Summary

Name LSM5
Full Name U6 snRNA-associated Sm-like protein LSm5
Synonyms LSM5_HUMAN |
Primary ID Q9Y4Y9
Links - -
Type protein
Relations 1
Function Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the preca ...
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Type: Score: Layout: SPV 
0.796LSM5U4/U6.U5 snRNP complex

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Relations
Regulator
Mechanism
target
score ℹ
+ LSM5form complex img/form-complex.png binding U4/U6.U5 snRNP complex 0.796
Identifier Residue Sequence Organism Cell Line
SIGNOR-270649 Homo sapiens
pmid sentence
The major spliceosomal building blocks are the U1, U2, U4/U6, and U5 small nuclear ribonucleoproteins (snRNPs). Each consists of a small nuclear RNA (snRNA) (or two, in the case of U4/U6), seven Sm proteins that form a ring (or seven Lsm proteins in the case of U6), and a variable number of snRNP-specific proteins (Fig. 1F) (Will and Lührmann 2011). Under splicing conditions, the U4/U6 and U5 snRNPs form a 25S U4/U6.U5 tri-snRNP, in which the U4 and U6 snRNAs are base-paired, forming a three-way junction.
Publications: 1 Organism: Homo Sapiens
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