3.0
Summary
| Name |  F11RView Modifications |
| Full Name | Junctional adhesion molecule A |
| Synonyms | JAM-A, Junctional adhesion molecule 1, JAM-1, Platelet F11 receptor, Platelet adhesion molecule 1, PAM-1 | JAM1, JCAM |
| Primary ID | Q9Y624 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840). |
phosphorylation