3.0
Summary
| Name |  TACC3View Modifications |
| Full Name | Transforming acidic coiled-coil-containing protein 3 |
| Synonyms | ERIC-1 | ERIC1 |
| Primary ID | Q9Y6A5 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476). |
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