| + |
HPRT1 | down-regulates quantity 
chemical modification
|
guanine |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280471 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10338013 |
Hypoxanthine phosphoribosyltransferase @HGPRTase; EC 2.4.2.8; hypoxanthine pyrophosphate phosphoribosyltransferase# is a purine salvage enzyme that catalyzes the reversible transfer of the 5-phosphoribosyl group between a-d-5-phosphoribosyl-1- pyrophosphate ~PRPP! and a purine base ~hypoxanthine or guanine! to form a purine nucleotide @inosine monophosphate ~IMP! or guanosine monophosphate ~GMP!#. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
guanine | up-regulates quantity 
precursor of
|
guanosine 5'-monophosphate(2-) |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280473 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 10338013 |
Hypoxanthine phosphoribosyltransferase @HGPRTase; EC 2.4.2.8; hypoxanthine pyrophosphate phosphoribosyltransferase# is a purine salvage enzyme that catalyzes the reversible transfer of the 5-phosphoribosyl group between a-d-5-phosphoribosyl-1- pyrophosphate ~PRPP! and a purine base ~hypoxanthine or guanine! to form a purine nucleotide @inosine monophosphate ~IMP! or guanosine monophosphate ~GMP!#. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
PNP | down-regulates quantity
chemical modification
|
guanine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280542 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35063692 |
Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine salvage pathway. Inosine and guanosine and the respective deoxynucleosides are substrates of this enzyme. Adenosine and deoxyadenosine are mainly deaminated by adenosine deaminase respectively to inosine and deoxyinosine which are in turn catabolized by PNP |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280546 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35063692 |
Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine salvage pathway. Inosine and guanosine and the respective deoxynucleosides are substrates of this enzyme. Adenosine and deoxyadenosine are mainly deaminated by adenosine deaminase respectively to inosine and deoxyinosine which are in turn catabolized by PNP |
|
| Publications: |
2 |
Organism: |
Homo Sapiens |
| + |
guanine | up-regulates quantity
precursor of
|
guanosine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280544 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35063692 |
Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine salvage pathway. Inosine and guanosine and the respective deoxynucleosides are substrates of this enzyme. Adenosine and deoxyadenosine are mainly deaminated by adenosine deaminase respectively to inosine and deoxyinosine which are in turn catabolized by PNP |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
guanine | up-regulates quantity
precursor of
|
2'-deoxyguanosine |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-280548 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 35063692 |
Purine nucleoside phosphorylase (PNP) is a key enzyme in the purine salvage pathway. Inosine and guanosine and the respective deoxynucleosides are substrates of this enzyme. Adenosine and deoxyadenosine are mainly deaminated by adenosine deaminase respectively to inosine and deoxyinosine which are in turn catabolized by PNP |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
4.0
guanine