SIGNOR 2.0

Programmatic Access

SIGNOR offers the following ways to access data programmatically through REST APIs

URL	Data Types	Parameters
/getData.php?	Interaction Data, tab-separated	id: MANDATORY – the ID of the searched entity (UniprotKB ID for proteins, PubChem ID for chemicals or small molecules, SIGNOR-ID for SIGNOR entities) organism: NON-MANDATORY (default = Homo sapiens) the organism (tax ID for either Homo sapiens, Mus musculus or Rattus norvegicus) the interactions take place in proteins type and level: NON-MANDATORY. Allows the user to search for a list of proteins and select which connection type (connect, all) and level (1,2,3).
Example: https://signor.uniroma2.it/getData.php?type=connect&proteins=P29317+Q06124%2CP04049%2CP15056&level=2
Example: https://signor.uniroma2.it/getData.php?organism=9606&id=P62258
/getUniprotIDs.php	List of all UniprotKB entities curated in SIGNOR interactions (by ID)	–
/getPathwayData.php	Pathway Data, tab-separated	pathway: the value identifies SIGNOR ID assigned to pathway. If used alone, it links to pathway information. In conjunction with other parameters, these will apply to the chosen pathway. description: does not take a value, links to pathway descriptions. If pathway perimeter is defined, shows only description for single pathway. relations: if no pathway is indicated, it shows all pathway relations. If a pathway is indicated and this parameter is added with no value, it will add pathway relations to result. To show only relations from a pathway, use "only" value for this parameter.
/API/getComplexData.php	ALL COMPLEX INFORMATION	-
/API/getHumanData.php	HUMAN-ONLY INTERACTION DATA	-
Examples: SINGLE Pathway Info: https://signor.uniroma2.it/getPathwayData.php?pathway=SIGNOR-MM SINGLE Pathway Relations: https://signor.uniroma2.it/getPathwayData.php?pathway=SIGNOR-MM&relations=only SINGLE Pathway Info + Relations: https://signor.uniroma2.it/getPathwayData.php?pathway=SIGNOR-MM&relations ALL Pathway Descriptions: https://signor.uniroma2.it/getPathwayData.php?description ALL Pathway Relations: https://signor.uniroma2.it/getPathwayData.php?relations ALL Pathway Data: https://signor.uniroma2.it/getPathwayData.php?description&relations