| + |
AMPD1 | up-regulates quantity 
chemical modification
|
ammonium |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269775 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 1631143 |
AMP deaminase (AMPD; EC 3.5.4.6) is encoded by a multigene family in mammals. The AMPD1 gene is expressed at high levels in skeletal muscle, where this enzyme is thought to play an important role in energy metabolism. AMP deaminase (AMPD; EC 3.5.4.6), an enzyme that catalyzes deamination of AMP to IMP, and the purine nucleotide cycle, of which AMPD is one component, play a central role in purine nucleotide interconversion in eukaryotic cells. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Tissue: |
Skeletal Muscle |
| + |
GLUL | down-regulates quantity 
chemical modification
|
ammonium |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267825 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30158707 |
Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. certain cell types express glutamine synthetase (GS; also called glutamate-ammonia ligase; GLUL), the enzyme capable of de novo glutamine production from glutamate and ammonia in an ATP and Mg2+/Mn2+ requiring reaction. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glutamine metabolism |
| + |
ammonium | up-regulates quantity
precursor of
|
L-glutamine zwitterion |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267823 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 30158707 |
Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. certain cell types express glutamine synthetase (GS; also called glutamate-ammonia ligase; GLUL), the enzyme capable of de novo glutamine production from glutamate and ammonia in an ATP and Mg2+/Mn2+ requiring reaction. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| Pathways: | Glutamine metabolism |
3.0
ammonium