| + |
D-thyroxine | up-regulates activity 
chemical activation
|
THR |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-270294 |
|
|
Homo sapiens |
Thyroid Epithelial Cell |
| pmid |
sentence |
| 6777394 |
The high levels of circulating D-T4 and presumably of circulating D-T3 originating from the peripheral conversion of D-T4 achieved after the chronic administration of D-T4 (Choloxin) may be responsible for a high degree of saturation of the human pituitary nuclear T3 receptors, thus resulting in the suppression of the TRH-induced TSH response. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-269878 |
|
|
Homo sapiens |
Thyroid Epithelial Cell |
| pmid |
sentence |
| 6777394 |
The high levels of circulating D-T4 and presumably of circulating D-T3 originating from the peripheral conversion of D-T4 achieved after the chronic administration of D-T4 (Choloxin) may be responsible for a high degree of saturation of the human pituitary nuclear T3 receptors, thus resulting in the suppression of the TRH-induced TSH response. |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-267802 |
|
|
Homo sapiens |
Thyroid Epithelial Cell |
| pmid |
sentence |
| 6777394 |
The high levels of circulating D-T4 and presumably of circulating D-T3 originating from the peripheral conversion of D-T4 achieved after the chronic administration of D-T4 (Choloxin) may be responsible for a high degree of saturation of the human pituitary nuclear T3 receptors, thus resulting in the suppression of the TRH-induced TSH response. |
|
| Publications: |
3 |
Organism: |
Homo Sapiens |
| + |
D-thyroxine | up-regulates activity
chemical activation
|
THRA |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-258402 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 6777394 |
The high levels of circulating D-T4 and presumably of circulating D-T3 originating from the peripheral conversion of D-T4 achieved after the chronic administration of D-T4 (Choloxin) may be responsible for a high degree of saturation of the human pituitary nuclear T3 receptors, thus resulting in the suppression of the TRH-induced TSH response. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
D-thyroxine | up-regulates activity
chemical activation
|
THRB |
0.8 |
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-258401 |
|
|
Homo sapiens |
Thyroid Epithelial Cell |
| pmid |
sentence |
| 6777394 |
The high levels of circulating D-T4 and presumably of circulating D-T3 originating from the peripheral conversion of D-T4 achieved after the chronic administration of D-T4 (Choloxin) may be responsible for a high degree of saturation of the human pituitary nuclear T3 receptors, thus resulting in the suppression of the TRH-induced TSH response. |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
3.0
D-thyroxine