| + |
Methylcrotonyl-CoA carboxylase complex | up-regulates activity
chemical modification
|
trans-3-methylglutaconyl-CoA(5-) |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281460 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17360195 |
The current study reports the use of baculovirus system to express functionally active human recombinant 3-methylcrotonyl-CoA carboxylase (MCCC), a heteromultimeric complex that is composed of alpha and beta subunits which are encoded by distinct genes. 3-Methylcrotonyl-CoA carboxylase (MCCC; EC 6.4.1.4)1 is a mitochondrial enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism in species including mammals, plants and bacteria |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |
| + |
3-methylbut-2-enoyl-CoA(4-) | up-regulates quantity
precursor of
|
trans-3-methylglutaconyl-CoA(5-) |
|
| Identifier |
Residue |
Sequence |
Organism |
Cell Line |
| SIGNOR-281462 |
|
|
Homo sapiens |
|
| pmid |
sentence |
| 17360195 |
The current study reports the use of baculovirus system to express functionally active human recombinant 3-methylcrotonyl-CoA carboxylase (MCCC), a heteromultimeric complex that is composed of alpha and beta subunits which are encoded by distinct genes. 3-Methylcrotonyl-CoA carboxylase (MCCC; EC 6.4.1.4)1 is a mitochondrial enzyme that catalyzes the conversion of 3-methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism in species including mammals, plants and bacteria |
|
| Publications: |
1 |
Organism: |
Homo Sapiens |