Relation Results

Summary

Name 7-[4-[4-(2,3-Dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Synonyms UNC0006, SCHEMBL253164, GTPL7651, NGCKUAWDNUFNBB-UHFFFAOYSA-N
IUPAC 7-[4-[4-(2,3-dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-one
Formula C24H29Cl2N3O2
Primary ID CID:56597938
Type chemical
Relations 1

Viewer

Type: Score: Layout: SPV 
0.87-[4-[4-(2,3-Dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-oneDRD2

Search Tools

Refine search:

  • by mechanism


  • by effect
  • by organism:


  • by tissue:


  • by cell-line

Relations
Regulator
Mechanism
target
score ℹ
+ 7-[4-[4-(2,3-Dichlorophenyl)-1,4-diazepan-1-yl]butoxy]-3,4-dihydro-1H-quinolin-2-oneup-regulates activity img/direct-activation.png chemical activation DRD2 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-258320 Homo sapiens HEK-293T Cell
pmid sentence
Through a robust diversity-oriented modification of the scaffold represented by aripiprazole (1), we discovered UNC9975 (2), UNC0006 (3), and UNC9994 (4) as unprecedented β-arrestin–biased D2R ligands. 
Publications: 1 Organism: Homo Sapiens
a simple tooltip