Relation Results

Summary

Name N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide
Synonyms 783348-36-7, MLN-120B, ml120b, N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide
IUPAC N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylpyridine-3-carboxamide
Formula C19H15ClN4O2
Primary ID CID:9929127
Type chemical
Relations 1

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Type: Score: Layout: SPV 
0.8N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamideIKBKB

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+ N-(6-Chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamidedown-regulates activity img/direct_inhibition.png chemical inhibition IKBKB 0.8
Identifier Residue Sequence Organism Cell Line
SIGNOR-258249 in vitro
pmid sentence
Our data set represents the most detailed comprehensive assessment of the reactivity of known and clinical kinase inhibitors across the kinome published to date. | The data also show that for at least 15 of the 27 kinases that are the primary, intended targets for the compounds tested and that are represented in the assay panel, selective inhibitors, as assessed by both absolute selectivity across the kinome and selectivity relative to the primary target, are among the 72 tested here.
Publications: 1 Organism: In Vitro
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