Summary

Name PSMD12
Full Name 26S proteasome non-ATPase regulatory subunit 12
Synonyms 26S proteasome regulatory subunit RPN5, 26S proteasome regulatory subunit p55 |
Primary ID O00232
Links - -
Type protein
Relations 1
Function Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

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Relations

Regulator Mechanism target score
+ form complex img/form-complex.png binding 26S Proteasome 0.913
Publications: 1 Organism: Homo Sapiens