| Name
|
 SLC28A1
|
| Full Name |
Sodium/nucleoside cotransporter 1 |
| Synonyms |
Concentrative nucleoside transporter 1, CNT 1, hCNT1, Na(+)/nucleoside cotransporter 1, Sodium-coupled nucleoside transporter 1, Solute carrier family 28 member 1 | CNT1 |
| Primary ID |
O00337 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
0 |
| Function |
Sodium-dependent and pyrimidine-selective transporter (PubMed:21998139). Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine). Transports uridine, cytidine, thymidine, and nucleoside-derived drugs (PubMed:21998139). Transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It may be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS). It has the following selective inhibition |
4.0