Summary

Name TRAF5
Full Name TNF receptor-associated factor 5
Synonyms RING finger protein 84 | RNF84, RNF84
Primary ID O00463
Links - -
Type protein
Relations 3
Function Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.

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Relations

Regulator Mechanism target score
+ up-regulates activity img/direct-activation.png binding TRAF5 0.613
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png ubiquitination TRAF5 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding TRAF5 0.596
Publications: 1 Organism: Homo Sapiens