4.0
Summary
| Name |  E2F3View Modifications |
| Full Name | Transcription factor E2F3 |
| Synonyms | E2F-3 | KIAA0075 |
| Primary ID | O00716 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F3 binds specifically to RB1 in a cell-cycle dependent manner. Inhibits adipogenesis, probably through the repression of CEBPA binding to its target gene promoters (By similarity). |
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phosphorylation