| Name
|
DYNC1I1
|
| Full Name |
Cytoplasmic dynein 1 intermediate chain 1 |
| Synonyms |
Cytoplasmic dynein intermediate chain 1, Dynein intermediate chain 1, cytosolic, DH IC-1 | DNCI1, DNCIC1 |
| Primary ID |
O14576 |
| Links |
- -  |
| Type |
protein |
| Relations |
0 |
| Function |
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores. |