Summary

Name TNFRSF13B
Full Name Tumor necrosis factor receptor superfamily member 13B
Synonyms Transmembrane activator and CAML interactor | TACI
Primary ID O14836
Links - -
Type protein
Relations 2
Function Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding TNFRSF13B 0.698
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding TNFRSF13B 0.775
Publications: 1 Organism: Homo Sapiens