4.0
Summary
| Name |  ANKRD28View Modifications |
| Full Name | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A |
| Synonyms | PP6-ARS-A, Serine/threonine-protein phosphatase 6 regulatory subunit ARS-A, Ankyrin repeat domain-containing protein 28, Phosphatase interactor targeting protein hnRNP K, PITK | KIAA0379 |
| Primary ID | O15084 |
| Links |  -  -  |
| Type | protein |
| Relations | 3 |
| Function | Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation. |
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Modifications Tables
Relations
| Regulator | Mechanism | target | score ℹ | |
|---|---|---|---|---|
| + | GSK3A | down-regulates activity 
phosphorylation
|
ANKRD28 | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | CAMK2D | down-regulates activity
phosphorylation
|
ANKRD28 | 0.2 |
| Publications: | 1 | Organism: | In Vitro | |
| + | ANKRD28 | up-regulates activity 
binding
|
PPP1CC | 0.443 |
| Publications: | 1 | Organism: | In Vitro | |