3.0
Summary
| Name |  TLR3
|
| Full Name | Toll-like receptor 3 |
| Synonyms | TLR3_HUMAN |
| Primary ID | O15455 |
| Links |  -  -  |
| Type | protein |
| Relations | 2 |
| Function | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. |
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transcriptional regulation
transcriptional regulation