Summary

Name PLXNB1
Full Name Plexin-B1
Synonyms Semaphorin receptor SEP | KIAA0407, PLXN5, SEP
Primary ID O43157
Links - -
Type protein
Relations 1
Function Receptor for SEMA4D (PubMed:19843518, PubMed:20877282, PubMed:21912513). Plays a role in GABAergic synapse development (By similarity). Mediates SEMA4A- and SEMA4D-dependent inhibitory synapse development (By similarity). Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton (PubMed:12196628, PubMed:15210733). Plays a role in axon guidance, invasive growth and cell migration (PubMed:12198496).

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Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png binding PLXNB1 0.803
Publications: 1 Organism: Homo Sapiens