Relation Results

Summary

Name RGS10
Full Name Regulator of G-protein signaling 10
Synonyms RGS10
Primary ID O43665
Links - -
Type protein
Relations 1
Function Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signa ...
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Type: Score: Layout: SPV 
0.335PRKACARGS10

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Relations
Regulator
Mechanism
target
score ℹ
+ PRKACAdown-regulates activity img/direct_inhibition.png phosphorylation RGS10 0.335
Identifier Residue Sequence Organism Cell Line
SIGNOR-109173 Ser176 QTAAKRAsRIYNT Homo sapiens
pmid sentence
We report in this study the acute functional regulation of rgs10 thru the specific and inducible phosphorylation of rgs10 protein at serine 168 by camp-dependent kinase a. This phosphorylation nullifies the rgs10 activity at the plasma membrane, which controls the g protein-dependent activation of the inwardly rectifying potassium channel.
Publications: 1 Organism: Homo Sapiens
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