Relation Results

Summary

Name ZBTB14
Full Name Zinc finger and BTB domain-containing protein 14
Synonyms Zinc finger protein 161 homolog, Zfp-161, Zinc finger protein 478, Zinc finger protein 5 homolog, ZF5, Zfp-5, hZF5 | ZFP161, ZNF478
Primary ID O43829
Links - -
Type protein
Relations 3
Function Transcriptional activator of the dopamine transporter (DAT), binding it's promoter at the consensus sequence 5'-CCTGCACAGTTCACGGA-3'. Binds to 5'-d(GC ...
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Type: Score: Layout: SPV 
0.20.2880.317ZBTB14NACC1MYC

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Relations
Regulator
Mechanism
target
score ℹ
+ ZBTB14up-regulates activity img/direct-activation.png binding ZBTB14 0.2
Identifier Residue Sequence Organism Cell Line
SIGNOR-220534 Homo sapiens
pmid sentence
ZF5, which we have cloned as a transcriptional repressor on the mouse c-myc promoter, has the POZ domain at the amino-terminus and the Kruppel-type zinc finger domain at the carboxy-terminus. We demonstrated that the POZ domain has a function mediating homomeric protein-protein interaction and this interaction requires the zinc finger domain.
Publications: 1 Organism: Homo Sapiens
+ NACC1up-regulates activity img/direct-activation.png binding ZBTB14 0.288
Identifier Residue Sequence Organism Cell Line
SIGNOR-226443 in vitro
pmid sentence
NAC1 potentiated ZF5 mediated repression in Gal4-DBD fusion transient assays. GST pulldown assays further confirmed protein–protein interactions between these proteins and NAC1.
Publications: 1 Organism: In Vitro
+ ZBTB14down-regulates quantity by repression img/indirect_inhibition.png transcriptional regulation MYC 0.317
Identifier Residue Sequence Organism Cell Line
SIGNOR-220537 Mus musculus
pmid sentence
ZF5, which we have cloned as a transcriptional repressor on the mouse c-myc promoter
Publications: 1 Organism: Mus Musculus
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