| Name
|
 PPP1R11
|
| Full Name |
E3 ubiquitin-protein ligase PPP1R11 |
| Synonyms |
Hemochromatosis candidate gene V protein, HCG V, Protein phosphatase inhibitor 3 | HCGV, TCTE5 |
| Primary ID |
O60927 |
| Links |
 -  -  |
| Type |
protein |
| Relations |
0 |
| Function |
Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901). Inhibitor of protein phosphatase 1 (PubMed:9843442). |
4.0